diff --git a/components/DataTable/src/DataTable/DataTable.cs b/components/DataTable/src/DataTable/DataTable.cs
index 65a3c1b81..f42df3e50 100644
--- a/components/DataTable/src/DataTable/DataTable.cs
+++ b/components/DataTable/src/DataTable/DataTable.cs
@@ -93,7 +93,11 @@ protected override Size MeasureOverride(Size availableSize)
                 // then invalidate the child arranges [don't re-measure and cause loop]...)
 
                 // For now, we'll just use the header content as a guideline to see if things work.
-                column.Measure(new Size(availableSize.Width - fixedWidth - autoSized, availableSize.Height));
+
+                // Avoid negative values when columns don't fit `availableSize`. Otherwise the `Size` constructor will throw.
+                double width = availableSize.Width - fixedWidth - autoSized;
+                width = Math.Max(width, 0);
+                column.Measure(new Size(width, availableSize.Height));
 
                 // Keep track of already 'allotted' space, use either the maximum child size (if we know it) or the header content
                 autoSized += Math.Max(column.DesiredSize.Width, column.MaxChildDesiredWidth);