diff --git a/dev-requirements/dev.txt b/dev-requirements/dev.txt
index a8715d57..e6f220e0 100644
--- a/dev-requirements/dev.txt
+++ b/dev-requirements/dev.txt
@@ -15,7 +15,7 @@ importlib-metadata==4.0.1
 iniconfig==1.1.1
 isodate==0.6.0
 isort==5.8.0
-Jinja2==2.11.3
+Jinja2==3.1.3
 lxml==4.9.1
 MarkupSafe==1.1.1
 mccabe==0.6.1
diff --git a/setup.py b/setup.py
index 475cae54..e1b9cfa1 100644
--- a/setup.py
+++ b/setup.py
@@ -61,9 +61,9 @@
         'six>=1.15.0, <2',
         'sympy>=1.9, <1.11',
         'zipp>=1.2.0, <2',
-        'Jinja2>=2.11.3, <3',
+        'Jinja2>=2.11.3, <4',
         'cellmlmanip>=0.3.6, <0.4',
-        'Jinja2>=2.11.3, <3',
+        'Jinja2>=2.11.3, <4',
     ],
     extras_require={
         'docs': [