From 5c865045d402d1aa0576242e9ec972ddc6e55bd0 Mon Sep 17 00:00:00 2001 From: Aleix Puig <94959119+aleixpuigb@users.noreply.github.com> Date: Fri, 17 Jan 2025 11:33:35 +0000 Subject: [PATCH 1/2] Fixes #2892 NTR diffuse bipolar 4a and 4b cells (#2900) Fixes #2892 NTR diffuse bipolar 4a and 4b cells The higly expressed genes are not added in logical axioms waiting for HCA feedback and NS-Forest markers. --- src/ontology/cl-edit.owl | 22 ++++++++++++++++++++++ 1 file changed, 22 insertions(+) diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl index b60fcc0af..1bba56e91 100644 --- a/src/ontology/cl-edit.owl +++ b/src/ontology/cl-edit.owl @@ -3049,6 +3049,8 @@ Declaration(Class(obo:CL_4033091)) Declaration(Class(obo:CL_4033092)) Declaration(Class(obo:CL_4033093)) Declaration(Class(obo:CL_4033094)) +Declaration(Class(obo:CL_4033095)) +Declaration(Class(obo:CL_4033096)) Declaration(Class(obo:CL_4040000)) Declaration(Class(obo:CL_4040001)) Declaration(Class(obo:CL_4040002)) @@ -32427,6 +32429,26 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35798993") Annotation(ob AnnotationAssertion(rdfs:label obo:CL_4033094 "age-associated B cell") SubClassOf(obo:CL_4033094 obo:CL_0000787) +# Class: obo:CL_4033095 (diffuse bipolar 4a cell) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31995762") Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") obo:IAO_0000115 obo:CL_4033095 "An ON bipolar cell that has high expression of DIRC3, KCNJ3, LINC01915, PTPRK compared with other bipolar cells.") +AnnotationAssertion(terms:contributor obo:CL_4033095 ) +AnnotationAssertion(terms:date obo:CL_4033095 "2025-01-14T13:48:42Z"^^xsd:dateTime) +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033095 "DB4a") +AnnotationAssertion(rdfs:label obo:CL_4033095 "diffuse bipolar 4a cell") +SubClassOf(obo:CL_4033095 obo:CL_0000749) +SubClassOf(obo:CL_4033095 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)) + +# Class: obo:CL_4033096 (diffuse bipolar 4b cell) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31995762") Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") obo:IAO_0000115 obo:CL_4033096 "An ON bipolar cell that has high expression of NOS1AP compared with other bipolar cells.") +AnnotationAssertion(terms:contributor obo:CL_4033096 ) +AnnotationAssertion(terms:date obo:CL_4033096 "2025-01-14T13:49:08Z"^^xsd:dateTime) +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033096 "DB4b") +AnnotationAssertion(rdfs:label obo:CL_4033096 "diffuse bipolar 4b cell") +SubClassOf(obo:CL_4033096 obo:CL_0000749) +SubClassOf(obo:CL_4033096 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606)) + # Class: obo:CL_4040000 (glial restricted tripotential precursor cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10719353") obo:IAO_0000115 obo:CL_4040000 "A glial precursor cell that generates oligodendrocytes and type-1 and type-2 astrocytes. It has been shown in some mammals that this cell type may express A2B5, nestin, FGFR-1, FGFR-2, FGFR-3, PLP, and DM-20 antigens. Unlike oligodendrocyte precursor cell, it does not initially express PDGFR-alpha and can differentiate into both type-1 and type-2 astrocytes.") From d6c900229cbc4526f2f1e5c934935fa2da62c7fd Mon Sep 17 00:00:00 2001 From: CEastwood <116108977+Caroline-99@users.noreply.github.com> Date: Fri, 17 Jan 2025 14:53:34 +0000 Subject: [PATCH 2/2] Fixes #2910 - NTR - tuft cell of pancreatic duct (#2913) * Fixes #2910 - NTR - tuft cell of pancreatic duct Fixes #2910 - Added a new term with textual and logical defs, synonyms and references. * updated textual definition and synonyms --- src/ontology/cl-edit.owl | 11 +++++++++++ 1 file changed, 11 insertions(+) diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl index 1bba56e91..f64f0e4a6 100644 --- a/src/ontology/cl-edit.owl +++ b/src/ontology/cl-edit.owl @@ -3148,6 +3148,7 @@ Declaration(Class(obo:CL_4052029)) Declaration(Class(obo:CL_4052030)) Declaration(Class(obo:CL_4052031)) Declaration(Class(obo:CL_4052032)) +Declaration(Class(obo:CL_4052035)) Declaration(Class(obo:CL_4052048)) Declaration(Class(obo:CL_4052049)) Declaration(Class(obo:CP_0000000)) @@ -33526,6 +33527,16 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") rdfs:comment AnnotationAssertion(rdfs:label obo:CL_4052032 "granzyme H-associated CD8 T cell") EquivalentClasses(obo:CL_4052032 ObjectIntersectionOf(obo:CL_0000909 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003490))) +# Class: obo:CL_4052035 (tuft cell of pancreatic duct) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30904566") Annotation(oboInOwl:hasDbXref "PMID:32717220") obo:IAO_0000115 obo:CL_4052035 "A tuft cell that is part of the epithelium of pancreatic duct. Present in humans and rats, this cell is absent in the murine pancreas under normal conditions but emerges during acinar-to-ductal metaplasia triggered by injury, inflammation, or oncogenic mutations. It modulates the immune response and protects against pancreatic ductal adenocarcinoma progression by producing suppressive eicosanoids, such as prostaglandin D2. A tuft cell in the pancreatic duct highly expresses the transcription factor POU2F3, which is essential for its development and presence.") +AnnotationAssertion(terms:contributor obo:CL_4052035 ) +AnnotationAssertion(terms:date obo:CL_4052035 "2025-01-16T11:50:08Z"^^xsd:dateTime) +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9749964") oboInOwl:hasExactSynonym obo:CL_4052035 "pancreatic brush cell") +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32717220") oboInOwl:hasExactSynonym obo:CL_4052035 "pancreatic tuft cell") +AnnotationAssertion(rdfs:label obo:CL_4052035 "tuft cell of pancreatic duct") +EquivalentClasses(obo:CL_4052035 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009970))) + # Class: obo:CL_4052048 (intercalated cell of salivary gland) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.")