[NTR] tuft cell of nasal cavity

[Caroline-99]

Please check that the term does not already exist by using the ontology search tool OLS:
https://www.ebi.ac.uk/ols4/ontologies/cl

Preferred term label
tuft cell of nasal cavity

Synonyms (add reference(s), please)
nasal tuft cell (exact synonym) - PMID: 38306414

Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)

A tuft cell that is part of the nasal cavity epithelium, located in both the respiratory and olfactory epithelia of the nose. It shares a core transcriptional profile with other tuft cells, including those in the trachea and intestine, expressing markers such as TRPM5, POU2F3, ChAT, AVIL, and eicosanoid biosynthetic enzymes like ALOX5AP and LTC4S. This cell plays key roles in chemosensation, lipid mediator production, immune responses, and epithelial homeostasis. It is more abundant in the nasal cavity than in the trachea. (PMID: 38306414).

PMID: 30379593
PMID: 38306414

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)
brush cell

Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)
nasal cavity epithelium

Your ORCID

Additional notes or concerns