diff --git a/tests/quantization/test_register_quantization_config.py b/tests/quantization/test_register_quantization_config.py
new file mode 100644
index 0000000000000..8e7f44a399ddf
--- /dev/null
+++ b/tests/quantization/test_register_quantization_config.py
@@ -0,0 +1,117 @@
+"""Tests register custom quantization config.
+
+See https://github.com/vllm-project/vllm/issues/11926 for more details.
+
+Run `pytest tests/quantization/test_register_quantization_config.py`.
+"""
+from typing import Any, Dict, List, Optional
+
+import pytest
+import torch
+import torch.nn.functional as F
+
+from vllm.model_executor.layers.linear import LinearBase  # noqa: E501
+from vllm.model_executor.layers.linear import UnquantizedLinearMethod
+from vllm.model_executor.layers.quantization import (
+    get_quantization_config, register_quantization_config)
+from vllm.model_executor.layers.quantization.base_config import (  # noqa: E501
+    QuantizationConfig)
+
+
+class FakeQuantLinearMethod(UnquantizedLinearMethod):
+    """Fake quantization linear method for per-token dynamic quantization."""
+
+    def __init__(self, num_bits: int = 8) -> None:
+        """Initialize the quantization method."""
+        super().__init__()
+        self.num_bits = num_bits
+
+    def apply(self,
+              layer: "torch.nn.Module",
+              x: "torch.Tensor",
+              bias: Optional["torch.Tensor"] = None) -> "torch.Tensor":
+        """Perform fake quantization before the linear layer."""
+
+        # Calculate the scales dynamically
+        max_val = torch.amax(x, dim=(0, -1), keepdims=True)
+        min_val = torch.amin(x, dim=(0, -1), keepdims=True)
+        scales = (max_val - min_val) / (2**self.num_bits - 1)
+
+        # Fake quantize the input
+        quant_x = torch.clamp(torch.round(x / scales), -2**(self.num_bits - 1),
+                              2**(self.num_bits - 1) - 1)
+        dequant_x = quant_x * scales
+
+        return F.linear(dequant_x, layer.weight, bias)
+
+
+@register_quantization_config("custom_quant")
+class CustomQuantConfig(QuantizationConfig):
+    """Custom quantization config for per-token dynamic fake quantization."""
+
+    def __init__(self, num_bits: int = 8) -> None:
+        """Initialize the quantization config."""
+        self.num_bits = num_bits
+
+    def get_name(self) -> str:
+        """Name of the quantization method."""
+        return "custom_quant"
+
+    def get_supported_act_dtypes(self) -> List["torch.dtype"]:
+        """List of supported activation dtypes."""
+        return [torch.float16, torch.bfloat16]
+
+    @classmethod
+    def get_min_capability(cls) -> int:
+        """Minimum GPU capability to support the quantization method."""
+        return -1
+
+    @staticmethod
+    def get_config_filenames() -> List[str]:
+        """List of filenames to search for in the model directory."""
+        return []
+
+    @classmethod
+    def from_config(cls, config: Dict[str, Any]) -> "CustomQuantConfig":
+        """Create a config class from the model's quantization config."""
+        return CustomQuantConfig(num_bits=config.get("num_bits", 8))
+
+    def get_quant_method(self, layer: "torch.nn.Module",
+                         prefix: str) -> Optional["FakeQuantLinearMethod"]:
+        """Get the quantize method to use for the quantized layer."""
+        if isinstance(layer, LinearBase):
+            return FakeQuantLinearMethod(num_bits=self.num_bits)
+        return None
+
+
+def test_register_quantization_config():
+    """Test register custom quantization config."""
+
+    # The quantization method `custom_quant` should be registered.
+    assert get_quantization_config("custom_quant") == CustomQuantConfig
+
+    # The quantization method `custom_quant` is already exists,
+    # should raise an error.
+    with pytest.raises(ValueError):
+        register_quantization_config("custom_quant")(CustomQuantConfig)
+
+
+@pytest.mark.parametrize(argnames="model",
+                         argvalues=[
+                             "meta-llama/Meta-Llama-3-8B-Instruct",
+                         ])
+def test_custom_quant(vllm_runner, model):
+    """Test infer with the custom quantization method."""
+    with vllm_runner(model_name=model,
+                     quantization="custom_quant",
+                     enforce_eager=True) as llm:
+
+        model = llm.model.llm_engine.model_executor.driver_worker.model_runner.model  # noqa: E501
+        layer = model.model.layers[0]
+        qkv_proj = layer.self_attn.qkv_proj
+
+        # Check the quantization method is FakeQuantLinearMethod
+        assert isinstance(qkv_proj.quant_method, FakeQuantLinearMethod)
+
+        output = llm.generate_greedy("Hello my name is", max_tokens=20)
+        assert output
diff --git a/vllm/model_executor/layers/quantization/__init__.py b/vllm/model_executor/layers/quantization/__init__.py
index caeb8b95e02f2..d2bde13fcf546 100644
--- a/vllm/model_executor/layers/quantization/__init__.py
+++ b/vllm/model_executor/layers/quantization/__init__.py
@@ -29,6 +29,45 @@
     "quark"
 ]
 
+# The customized quantization methods which will be added to this dict.
+_CUSTOMIZED_METHOD_TO_QUANT_CONFIG = {}
+
+
+def register_quantization_config(quantization: str):
+    """Register a customized vllm quantization config.
+
+    When a quantization method is not supported by vllm, you can register a customized
+    quantization config to support it.
+
+    Args:
+        quantization (str): The quantization method name.
+
+    Examples:
+        >>> from vllm.model_executor.layers.quantization import register_quantization_config
+        >>> from vllm.model_executor.layers.quantization import get_quantization_config
+        >>> from vllm.model_executor.layers.quantization.base_config import QuantizationConfig
+        >>>
+        >>> @register_quantization_config("my_quant")
+        ... class MyQuantConfig(QuantizationConfig):
+        ...     pass
+        >>>
+        >>> get_quantization_config("my_quant")
+        <class 'MyQuantConfig'>
+    """  # noqa: E501
+
+    def _wrapper(quant_config_cls):
+        if quantization in QUANTIZATION_METHODS:
+            raise ValueError(
+                f"The quantization method `{quantization}` is already exists.")
+        if not issubclass(quant_config_cls, QuantizationConfig):
+            raise ValueError("The quantization config must be a subclass of "
+                             "`QuantizationConfig`.")
+        _CUSTOMIZED_METHOD_TO_QUANT_CONFIG[quantization] = quant_config_cls
+        QUANTIZATION_METHODS.append(quantization)
+        return quant_config_cls
+
+    return _wrapper
+
 
 def get_quantization_config(quantization: str) -> Type[QuantizationConfig]:
     if quantization not in QUANTIZATION_METHODS:
@@ -84,6 +123,8 @@ def get_quantization_config(quantization: str) -> Type[QuantizationConfig]:
         "ipex": IPEXConfig,
         "quark": QuarkConfig
     }
+    # Update the `method_to_config` with customized quantization methods.
+    method_to_config.update(_CUSTOMIZED_METHOD_TO_QUANT_CONFIG)
 
     return method_to_config[quantization]