diff --git a/nicegui/air.py b/nicegui/air.py
index ffa8233f0..e7c249e96 100644
--- a/nicegui/air.py
+++ b/nicegui/air.py
@@ -59,6 +59,7 @@ async def _handle_http(data: Dict[str, Any]) -> Dict[str, Any]:
                 content=data['body'],
             )
             response = await self.client.send(request)
+            self.client.cookies.clear()
             instance_id = data['instance-id']
             content = response.content.replace(
                 b'const extraHeaders = {};',