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Merge branch 'master' into 2909-ntr-tuft-cell-of-thymus
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Caroline-99 committed Jan 17, 2025
2 parents a12af28 + d6c9002 commit 5b2556a
Showing 1 changed file with 33 additions and 0 deletions.
33 changes: 33 additions & 0 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -3049,6 +3049,8 @@ Declaration(Class(obo:CL_4033091))
Declaration(Class(obo:CL_4033092))
Declaration(Class(obo:CL_4033093))
Declaration(Class(obo:CL_4033094))
Declaration(Class(obo:CL_4033095))
Declaration(Class(obo:CL_4033096))
Declaration(Class(obo:CL_4040000))
Declaration(Class(obo:CL_4040001))
Declaration(Class(obo:CL_4040002))
Expand Down Expand Up @@ -3146,6 +3148,7 @@ Declaration(Class(obo:CL_4052029))
Declaration(Class(obo:CL_4052030))
Declaration(Class(obo:CL_4052031))
Declaration(Class(obo:CL_4052032))
Declaration(Class(obo:CL_4052035))
Declaration(Class(obo:CL_4052034))
Declaration(Class(obo:CL_4052048))
Declaration(Class(obo:CL_4052049))
Expand Down Expand Up @@ -32429,6 +32432,26 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35798993") Annotation(ob
AnnotationAssertion(rdfs:label obo:CL_4033094 "age-associated B cell")
SubClassOf(obo:CL_4033094 obo:CL_0000787)

# Class: obo:CL_4033095 (diffuse bipolar 4a cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31995762") Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") obo:IAO_0000115 obo:CL_4033095 "An ON bipolar cell that has high expression of DIRC3, KCNJ3, LINC01915, PTPRK compared with other bipolar cells.")
AnnotationAssertion(terms:contributor obo:CL_4033095 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033095 "2025-01-14T13:48:42Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033095 "DB4a")
AnnotationAssertion(rdfs:label obo:CL_4033095 "diffuse bipolar 4a cell")
SubClassOf(obo:CL_4033095 obo:CL_0000749)
SubClassOf(obo:CL_4033095 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_4033096 (diffuse bipolar 4b cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31995762") Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") obo:IAO_0000115 obo:CL_4033096 "An ON bipolar cell that has high expression of NOS1AP compared with other bipolar cells.")
AnnotationAssertion(terms:contributor obo:CL_4033096 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:date obo:CL_4033096 "2025-01-14T13:49:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2023.11.07.566105") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033096 "DB4b")
AnnotationAssertion(rdfs:label obo:CL_4033096 "diffuse bipolar 4b cell")
SubClassOf(obo:CL_4033096 obo:CL_0000749)
SubClassOf(obo:CL_4033096 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_9606))

# Class: obo:CL_4040000 (glial restricted tripotential precursor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10719353") obo:IAO_0000115 obo:CL_4040000 "A glial precursor cell that generates oligodendrocytes and type-1 and type-2 astrocytes. It has been shown in some mammals that this cell type may express A2B5, nestin, FGFR-1, FGFR-2, FGFR-3, PLP, and DM-20 antigens. Unlike oligodendrocyte precursor cell, it does not initially express PDGFR-alpha and can differentiate into both type-1 and type-2 astrocytes.")
Expand Down Expand Up @@ -33506,6 +33529,16 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") rdfs:comment
AnnotationAssertion(rdfs:label obo:CL_4052032 "granzyme H-associated CD8 T cell")
EquivalentClasses(obo:CL_4052032 ObjectIntersectionOf(obo:CL_0000909 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003490)))

# Class: obo:CL_4052035 (tuft cell of pancreatic duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30904566") Annotation(oboInOwl:hasDbXref "PMID:32717220") obo:IAO_0000115 obo:CL_4052035 "A tuft cell that is part of the epithelium of pancreatic duct. Present in humans and rats, this cell is absent in the murine pancreas under normal conditions but emerges during acinar-to-ductal metaplasia triggered by injury, inflammation, or oncogenic mutations. It modulates the immune response and protects against pancreatic ductal adenocarcinoma progression by producing suppressive eicosanoids, such as prostaglandin D2. A tuft cell in the pancreatic duct highly expresses the transcription factor POU2F3, which is essential for its development and presence.")
AnnotationAssertion(terms:contributor obo:CL_4052035 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052035 "2025-01-16T11:50:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9749964") oboInOwl:hasExactSynonym obo:CL_4052035 "pancreatic brush cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32717220") oboInOwl:hasExactSynonym obo:CL_4052035 "pancreatic tuft cell")
AnnotationAssertion(rdfs:label obo:CL_4052035 "tuft cell of pancreatic duct")
EquivalentClasses(obo:CL_4052035 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009970)))

# Class: obo:CL_4052034 (tuft cell of thymus)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30904566") Annotation(oboInOwl:hasDbXref "PMID:36961668") Annotation(oboInOwl:hasDbXref "PMID:35668088") Annotation(oboInOwl:hasDbXref "PMID:36351364") obo:IAO_0000115 obo:CL_4052034 "A tuft cell that is part of the medullary epithelium of the thymus, characterized by lateral microvilli and specific markers, including L1CAM in both mice (Zhang et al., 2022) and humans (Sun et al., 2023), as well as MHC II in mice (Kotas et al., 2023). This cell is pivotal in immune functions such as antigen presentation, central tolerance, and type 2 immunity. A tuft cell in the thymus exhibits characteristics of both a medullary thymic epithelial cell (mTEC) and a peripheral tuft cell. Its development is governed by transcription factors such as POU2F3.")
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