[NTR] tuft cell of pancreatic duct

[Caroline-99]

Please check that the term does not already exist by using the ontology search tool OLS:
https://www.ebi.ac.uk/ols4/ontologies/cl

Preferred term label
tuft cell of pancreatic duct epithelium

Synonyms (add reference(s), please)
pancreatic duct tuft cell
pancreatic brush cell (PMID: 9749964) (exact or broad ?)
brush cell of pancreas (exact or broad?)
tuft cell of pancreatic duct epithelium

Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)
A tuft cell that is part of the epithelium of pancreatic duct.Unlike in humans and rats, this cell is absent in the murine pancreas under normal conditions but emerges during acinar-to-ductal metaplasia triggered by injury, inflammation, or oncogenic mutations. It modulates the immune response and protects against pancreatic ductal adenocarcinoma progression by producing suppressive eicosanoids like prostaglandin D2. The transcription factor POU2F3 is essential for its development and presence.

PMID: 30904566
doi:/10.1101/2019.12.19.882985

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)
brush cell

Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)
epithelium of pancreatic duct

Your ORCID

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