M cell and FAE partonomy update #2897
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@@ -9457,7 +9457,7 @@ SubClassOf(obo:CL_0000676 obo:CL_0000378) | |
| AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:CL_0000677 "Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules.") | ||
| AnnotationAssertion(rdfs:label obo:CL_0000677 "gut absorptive cell") | ||
| SubClassOf(obo:CL_0000677 obo:CL_0000000) | ||
| SubClassOf(obo:CL_0000677 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004693)) | ||
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There was a problem hiding this comment. gut absorptive cell is a grouping term for all enterocytes so it is not restricted to Peyer's patch epithelium (UBERON_0004693). I suggest changing it back to being part of intestinal epithelium (UBERON_0001277). There was a problem hiding this comment. updated as suggested |
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| # Class: obo:CL_0000678 (commissural neuron) | ||
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@@ -9506,7 +9506,7 @@ AnnotationAssertion(rdfs:label obo:CL_0000682 "M cell of gut") | |
| SubClassOf(obo:CL_0000682 obo:CL_0000066) | ||
| SubClassOf(obo:CL_0000682 obo:CL_0000473) | ||
| SubClassOf(obo:CL_0000682 obo:CL_0000627) | ||
| SubClassOf(obo:CL_0000682 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004693)) | ||
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There was a problem hiding this comment. This looks good. You could also consider classifying M cells as part of follicle associated epithelium rather than part of Peyer's patch epithelium (PMID: 18081850) but either terms would work. There was a problem hiding this comment. keeping as is as this was the change David requested |
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| # Class: obo:CL_0000683 (ependymoglial cell) | ||
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I cannot see any changes to FAE (follicle associated enterocyte) - I believe it should be EquivalentTo enterocyte and part of some follicle associated epithelium. The uberon term will need to be imported into CL.
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FAE has the anonymous ancestor part of some peyer's patch epithelium which is the edit requested
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As agreed with @JABelfiore,
part ofsome follicle associated epithelium will be added as a subclass to follicle associated epithelium enterocyte.