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Fixes #2906 NTR- tuft cell of duodenum #2911

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Fixes #2906 NTR- tuft cell of duodenum #2911

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12 changes: 12 additions & 0 deletions src/ontology/cl-edit.owl
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Original file line number Diff line number Diff line change
Expand Up @@ -3146,6 +3146,7 @@ Declaration(Class(obo:CL_4052029))
Declaration(Class(obo:CL_4052030))
Declaration(Class(obo:CL_4052031))
Declaration(Class(obo:CL_4052032))
Declaration(Class(obo:CL_4052033))
Declaration(Class(obo:CL_4052048))
Declaration(Class(obo:CL_4052049))
Declaration(Class(obo:CP_0000000))
Expand Down Expand Up @@ -33504,6 +33505,17 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") rdfs:comment
AnnotationAssertion(rdfs:label obo:CL_4052032 "granzyme H-associated CD8 T cell")
EquivalentClasses(obo:CL_4052032 ObjectIntersectionOf(obo:CL_0000909 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003490)))

# Class: obo:CL_4052033 (tuft cell of duodenum)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:22527717") Annotation(oboInOwl:hasDbXref "PMID:32307399") Annotation(oboInOwl:hasDbXref "PMID:32925177") obo:IAO_0000115 obo:CL_4052033 "A tuft cell that is part of the duodenal epithelium. This cell contributes to mucosal defense by acting as a chemosensory sentinel, detecting luminal stimuli (Akiba et al., 2020). Its presence in the duodenum suggests a potential role in protecting the mucosa from acidic content coming from the stomach Gerbe et al., 2012).")
AnnotationAssertion(terms:contributor obo:CL_4052033 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052033 "2025-01-16T10:37:49Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32307399") oboInOwl:hasExactSynonym obo:CL_4052033 "duodenal tuft cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4052033 "tuft cell of duodenal epithelium")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32307399") rdfs:comment obo:CL_4052033 "In pediatric celiac disease and duodenal ulcers, duodenal tuft cell numbers are significantly reduced compared to healthy controls, suggesting that their loss may contribute to prolonged inflammation and compromised mucosal integrity. In acute duodenitis, tuft cell counts vary, with severe inflammation linked to lower numbers.")
AnnotationAssertion(rdfs:label obo:CL_4052033 "tuft cell of duodenum")
EquivalentClasses(obo:CL_4052033 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008346)))

# Class: obo:CL_4052048 (intercalated cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.")
Expand Down
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