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type 3 mucosal glia #2948

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12 changes: 11 additions & 1 deletion src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -3117,6 +3117,7 @@ Declaration(Class(obo:CL_4047035))
Declaration(Class(obo:CL_4047037))
Declaration(Class(obo:CL_4047040))
Declaration(Class(obo:CL_4047043))
Declaration(Class(obo:CL_4047045))
Declaration(Class(obo:CL_4047051))
Declaration(Class(obo:CL_4047052))
Declaration(Class(obo:CL_4047101))
Expand Down Expand Up @@ -33175,14 +33176,23 @@ SubClassOf(obo:CL_4047040 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_001236

# Class: obo:CL_4047043 (type 1 submucosal plexus glia)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fncel.2023.1170309") Annotation(oboInOwl:hasDbXref "PMID:28487635") Annotation(oboInOwl:hasDbXref "PMID:33731961") obo:IAO_0000115 obo:CL_4047043 "An enteric glial cell that is associated with neuron cell bodies within submucosal ganglia of the gastrointestinal tract. This cell is located in the submucosa, a layer of connective tissue beneath the intestinal mucosa. This cell plays a role in modulating secretomotor neuron activity and contributes to the regulation of digestive fluid secretion and absorption.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fncel.2023.1170309") Annotation(oboInOwl:hasDbXref "PMID:28487635") Annotation(oboInOwl:hasDbXref "PMID:33731961") obo:IAO_0000115 obo:CL_4047043 "An enteric glial cell that is associated with neuron cell bodies within submucosal ganglia of the gastrointestinal tract. This cell plays a role in modulating secretomotor neuron activity and contributes to the regulation of digestive fluid secretion and absorption.")
AnnotationAssertion(terms:contributor obo:CL_4047043 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047043 "2025-02-10T17:02:28Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33731961") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4047043 "type I SMP")
AnnotationAssertion(rdfs:label obo:CL_4047043 "type 1 submucosal plexus glia")
SubClassOf(obo:CL_4047043 obo:CL_4040002)
SubClassOf(obo:CL_4047043 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009566))

# Class: obo:CL_4047045 (type 3 mucosal glia)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25161129") Annotation(oboInOwl:hasDbXref "PMID:33731961") Annotation(oboInOwl:hasDbXref "PMID:37153631") Annotation(oboInOwl:hasDbXref "PMID:38957473") obo:IAO_0000115 obo:CL_4047045 "An enteric glial cell located in the lamina propria of the intestinal mucosa. This cell typically has four major processes and is positioned in close proximity to the intestinal epithelium. This cell plays important roles in maintaining gut barrier function, regulating intestinal homeostasis, and mediating interactions between the enteric nervous system and the immune system.")
AnnotationAssertion(terms:contributor obo:CL_4047045 <https://orcid.org/0009-0005-7919-4905>)
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I think the second sentence is appliable to all enteroglial cells.

AnnotationAssertion(terms:date obo:CL_4047045 "2025-02-11T12:39:11Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047045 "type 3 mucosal glia")
SubClassOf(obo:CL_4047045 obo:CL_4040002)
SubClassOf(obo:CL_4047045 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000030))

# Class: obo:CL_4047051 (small intestine BEST4+ enterocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24223998") Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_4047051 "An enterocyte of the human small intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels. These enterocytes have a disinctive transcriptomic profile and are scattered through the small intestine epithelium.")
Expand Down