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Fixes #2910 - NTR - tuft cell of pancreatic duct #2913

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merged 3 commits into from
Jan 17, 2025
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Fixes #2910 - NTR - tuft cell of pancreatic duct #2913

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Fixes #2910 - NTR - tuft cell of pancreatic duct
Caroline-99 Jan 16, 2025
315c087
updated textual definition and synonyms
Caroline-99 Jan 17, 2025
e9f790a
Merge branch 'master' into 2910-ntr-tuft-cell-of-pancreatic-duct
Caroline-99 Jan 17, 2025
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13 changes: 13 additions & 0 deletions src/ontology/cl-edit.owl
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Original file line number Diff line number Diff line change
Expand Up @@ -3146,6 +3146,7 @@ Declaration(Class(obo:CL_4052029))
Declaration(Class(obo:CL_4052030))
Declaration(Class(obo:CL_4052031))
Declaration(Class(obo:CL_4052032))
Declaration(Class(obo:CL_4052035))
Declaration(Class(obo:CL_4052048))
Declaration(Class(obo:CL_4052049))
Declaration(Class(obo:CP_0000000))
Expand Down Expand Up @@ -33504,6 +33505,18 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") rdfs:comment
AnnotationAssertion(rdfs:label obo:CL_4052032 "granzyme H-associated CD8 T cell")
EquivalentClasses(obo:CL_4052032 ObjectIntersectionOf(obo:CL_0000909 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003490)))

# Class: obo:CL_4052035 (tuft cell of pancreatic duct)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30904566") Annotation(oboInOwl:hasDbXref "doi:/10.1101/2019.12.19.882985") obo:IAO_0000115 obo:CL_4052035 "A tuft cell that is part of the epithelium of pancreatic duct. Present in humans and rats, this cell is absent in the murine pancreas under normal conditions but emerges during acinar-to-ductal metaplasia triggered by injury, inflammation, or oncogenic mutations. It modulates the immune response and protects against pancreatic ductal adenocarcinoma progression by producing suppressive eicosanoids, such as prostaglandin D2. The transcription factor POU2F3 is essential for its development and presence.")
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AnnotationAssertion(terms:contributor obo:CL_4052035 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052035 "2025-01-16T11:50:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4052035 "brush cell of pancreas")
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In thi article it states about the change of nomenclature from brush to tuft in the pancreatic duct context: PMID:37182665

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I have removed all synonyms with no references ( I was only adding them to remain consistent with the existing tuft cell terms, but I agree with you—there’s no need for them). I have not changed 'pancreatic brush cell' since it has a reference and has been used previously. Please let me know if you would like me to change anything else ? Thank you

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9749964") oboInOwl:hasExactSynonym obo:CL_4052035 "pancreatic brush cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4052035 "pancreatic duct tuft cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4052035 "tuft cell of pancreatic duct epithelium")
AnnotationAssertion(rdfs:label obo:CL_4052035 "tuft cell of pancreatic duct")
EquivalentClasses(obo:CL_4052035 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009970)))

# Class: obo:CL_4052048 (intercalated cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.")
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